The Substance

Name: The Substance
Released: 2024
Cast: Demi Moore, Margaret Qualley, Dennis Quaid, Edward Hamilton-Clark, Gore Abrams

2024

A fading celebrity decides to use a black market drug, a cell-replicating substance that temporarily creates a younger, better version of herself.

Scores

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TMDB film score

7.1/10

External film audience average — not ActorRating users

0 of 113 performances rated

Performances

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Demi Moore

as Elisabeth

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Margaret Qualley

as Sue

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Dennis Quaid

as Harvey

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Edward Hamilton-Clark

as Fred

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Gore Abrams

as Oliver

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Oscar Lesage

as Troy

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Christian Erickson

as Man at Diner

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Robin Greer

as Male Nurse

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Tom Morton

as Doctor

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Hugo Diego Garcia

as Diego - Boyfriend

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Daniel Knight

as Casting Director

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Jonathon Carley

as Assistant Casting Director

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Jiselle Henderkott

as Girl Auditioning / New Year's Eve Show Dancer

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Akil Wingate

as TV Host

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Jordan Ford Silver

as Assistant Director - Pump It Up Show

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Oscar Salem

as 2nd Assistant Director - Pump It Up Show

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Viviane Bossina

as Sue's Assistant

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Matthew Luret

as Floor Runner

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Jana Bittnerová

as Maria

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Olivier Raynal

as Alan - 2nd Agent

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Tiffany Hofstetter

as Stylist

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Nicolas Royer

as Guy in the Elevator

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Nathan Rippy

as Assistant Director - New Year's Eve Show

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Manon Arizmendi

as Little Girl - New Year's Eve Show

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Virginie Kotlinski

as Mother - New Year's Eve Show

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Brett Gillen

as Director of Photography - New Year's Eve Show

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Charlotte Marquardt

as Screaming Woman

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Léa Hengl

as Screaming Woman

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Gaëlle Raymond

as Screaming Woman

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Claire Lemaire

as Screaming Woman

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Lila Boughoufala

as Screaming Woman

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Aurélien Lorgnier

as Screaming Man

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Ivan Sellier

as Screaming Man

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Philip Schurer

as Screaming Man

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Christian Bourmier

as Shareholder

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Martin Graham

as Shareholder

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Christian Bordeleau

as Shareholder

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Patrick Hamel

as Shareholder

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Didier Dhondt

as Shareholder

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Jacques-Yves Dorges

as Shareholder

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Jean-Claude Matthey

as Shareholder

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Olivier Jarcin

as Shareholder

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Jean-Luc Magneron

as Shareholder

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Charlotte Murray

as Allison - Diner Waitress

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Aaron Kahn

as Greeting Person

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Gabriela Arnon

as Greeting Person

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Nancy Josephson Lahoussine

as Greeting Person

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Andrew Eldridge

as Greeting Person

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Denise Powers

as Greeting Person

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Bryan Jones

as Greeting Person

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Adam Carage

as Happy Birthday Person

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Maria McClurg

as Happy Birthday Person

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Andrew Desmond

as Happy Birthday Person

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Rebecca Lafont

as Happy Birthday Person

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Laura Puech

as Isabella

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Ryan Chidester

as Stagehand

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Cécile Vogt

as Elisabeth (Young) - Walk of Fame / Pump It Up Show Dancer

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Yannick Guérin

as Clumsy Burger Guy - Walk of Fame

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Jean Miel

as Worker Walk of Fame

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Paul Descoings

as Worker Walk of Fame

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Benoit Lévêque

as Worker Walk of Fame

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Arthur Molinet

as Cocktail Bartender

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Manon Sachot

as Cocktail Lounge Couple

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Bastien Jorelle

as Cocktail Lounge Couple

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Kelly Hoarau

as Female Assistant - Towel

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Michel Juskiewicz

as George - Harvey's Friend

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Louise Greggory

as Restaurant Waitress

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Christophe Sartirano

as Guy Looking at Sue

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Florent Torres

as Guy Looking at Sue

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Romain Caldeira

as Billboard Technician

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Barthelemy Thomas

as Billboard Technician

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Axel Baille

as Photographer

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Ashley Lambert

as Additional Voices (voice)

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Ranjani Brow

as Additional Voices (voice)

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Chase Fein

as Additional Voices (voice)

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Shane Sweet

as Additional Voices (voice)

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William Calvert

as Additional Voices (voice)

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Michael Corbett

as Additional Voices (voice)

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Stephen Apostolina

as Additional Voices (voice)

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Yann Bean

as The Substance (voice)

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Audjyan Alcide

as Pump It Up Show Dancer

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Jonathan Jenvrin

as Pump It Up Show Dancer

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Mimi Maury

as Pump It Up Show Dancer

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Amelye Solange

as Pump It Up Show Dancer

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Kévin Table

as Pump It Up Show Dancer

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Laura Boera

as Sparkle Your Life Show Dancer

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Cissy Duc

as Sparkle Your Life Show Dancer

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Sophie Mercier

as Sparkle Your Life Show Dancer

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Marie Valton

as Sparkle Your Life Show Dancer

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Katrina Budzynski

as New Year's Eve Show Dancer

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Alicia Maury

as New Year's Eve Show Dancer

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Megane Adamik

as New Year's Eve Show Dancer

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Annalisa Pagnotta

as New Year's Eve Show Dancer

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Maelle Dantigny

as New Year's Eve Show Dancer

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Aleksandra Kedzierska Fontaine

as New Year's Eve Show Dancer

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Pauline Sagetat

as New Year's Eve Show Dancer

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Agustina Fitzsimons

as New Year's Eve Show Dancer

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Elena Shcheglova

as New Year's Eve Show Dancer

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Eve Marchant

as New Year's Eve Show Dancer

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Lola Donati

as New Year's Eve Show Dancer

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Kate Matthews

as New Year's Eve Show Dancer

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Ophélie Jonard

as New Year's Eve Show Dancer

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Pauline Richard

as New Year's Eve Show Dancer

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Laureen Cappelliez

as New Year's Eve Show Dancer

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Daria Panchenko

as New Year's Eve Show Dancer

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Delphine Beaulieu

as New Year's Eve Show Dancer

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Victoria Brun

as New Year's Eve Show Dancer

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Cara Chapman

as New Year's Eve Show Dancer

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Katharine Matthews

as New Year's Eve Show Dancer

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Alexandra Faget

as New Year's Eve Show Dancer

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Clémence Juville

as New Year's Eve Show Dancer

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Margot L'Entete

as New Year's Eve Show Dancer

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Hillary Sukhonos

as New Year's Eve Show Dancer